Side effects
What the product labels and trials report about common side effects, and the warning signs that mean calling your prescriber — without guesswork about what is "normal" for you.
Side effects
Nausea on GLP-1 medications
How often nausea and vomiting were reported with semaglutide and tirzepatide in the trials behind their labels, what the labels say about timing, and when to call your prescriber.
Side effects
Constipation on GLP-1 medications
How often constipation was reported with semaglutide and tirzepatide, how long it lasted in trials, what a 2025 nutrition advisory suggests, and the warning signs to act on.
Side effects
Diarrhea on GLP-1 medications
How often diarrhea was reported with semaglutide and tirzepatide, how long it lasted in trials, and why dehydration is the thing to watch.
Side effects
Fatigue on GLP-1 medications
What the labels report about tiredness with semaglutide and tirzepatide, the limits of that evidence, and the symptoms that point to something else.
Side effects
Hair loss on GLP-1 medications
How often hair loss was reported, who reported it more, what the labels link it to, and what two 2026 reviews found.
Side effects
Injection-site reactions
Redness, itching or bruising where you inject: how often the labels report it, what a 2026 meta-analysis found, and the signs of a serious allergic reaction.
Side effects
Gallbladder and pancreas warning signs
What the labels and studies say about gallbladder disease and pancreatitis with GLP-1 medications, and the symptoms that mean calling right away.
Side effects
When to call your prescriber
The warning signs the US Medication Guides list for semaglutide and tirzepatide, in one place — and which ones mean getting help right away.