Practical · US & Canada

Storing your medication

Pending medical review

By Joshua Nichvolodoff · Fact-checked against sources November 2, 2026 · Next review due May 1, 2027

Clinical review: not yet reviewed by a clinician. How review works · Editorial policy

Storage rules come from each product's label and differ between pens, vials and tablets — and between the US and Canada. Here is what each label says.

Time out of the fridge, by product (US labels)

Room-temperature limits in current US labels[1][5][3][2][6][4]
ItemOut of the fridgeNotes
Ozempic pen (after first use)56 days at 15–30°C (59–86°F), or in the fridgeKeep the cap on; store without a needle attached
Wegovy single-dose penUp to 28 days at 8–30°C, before removing the capKeep in the carton; protect from light
Zepbound / Mounjaro single-dose pen or vialUp to 21 days, not above 30°C (86°F)Don't put back in the fridge once at room temperature
Zepbound / Mounjaro KwikPen or multi-dose vialUnopened: up to 30 days, not above 30°COnce opened: discard after 30 days or 4 weekly doses
Wegovy tabletsStore at 20–25°COriginal bottle, dry place
RybelsusStore at 20–25°C (brief 15–30°C allowed)Original bottle, away from moisture
Summarized from each label's storage section. Check the label that came with your product.

In Canada

The Canadian Ozempic monograph says that after first use the pen can be kept below 30°C or in the fridge for 8 weeks, with the cap on to protect from light[7]. The Canadian Zepbound KwikPen monograph allows up to 30 days unrefrigerated at not above 30°C, and says to discard the pen after four weekly doses[8]. For other products, check your Canadian monograph or ask your pharmacist.

Heat, light and freezing

The labels say not to freeze injectable GLP-1 medicines and to protect them from heat and light — keeping them in the carton or with the cap on[1][2]. If a pen has been frozen or overheated, ask your pharmacist before using it.

General information from product labels, not medical advice.

Log each dose and see when the next one is due, on your device. Open my tracker or browse the other guides.

Sources

  1. OZEMPIC (semaglutide) injection — prescribing information (revised 05/2026). U.S. Food and Drug Administration, May 2026. https://www.accessdata.fda.gov/drugsatfda_docs/label/2026/209637s038lbl.pdf. Accessed November 2, 2026. Back to the text
  2. ZEPBOUND (tirzepatide) injection — prescribing information, Medication Guide and Instructions for Use (revised 02/2026). U.S. Food and Drug Administration, February 2026. https://www.accessdata.fda.gov/drugsatfda_docs/label/2026/217806s042lbl.pdf. Accessed November 2, 2026. Back to the text
  3. WEGOVY (semaglutide) injection and tablets — current label (revised 6/2026). DailyMed (U.S. National Library of Medicine), June 2026. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=ee06186f-2aa3-4990-a760-757579d8f77b. Accessed November 2, 2026. Back to the text
  4. RYBELSUS (semaglutide) tablets — prescribing information (revised 10/2025). U.S. Food and Drug Administration, October 2025. https://www.accessdata.fda.gov/drugsatfda_docs/label/2025/213051s024%2Cs028s029lbl.pdf. Accessed November 2, 2026. Back to the text
  5. WEGOVY (semaglutide) injection — prescribing information and Medication Guide (revised 08/2025). U.S. Food and Drug Administration, August 2025. https://www.accessdata.fda.gov/drugsatfda_docs/label/2025/215256s024lbl.pdf. Accessed November 2, 2026. Back to the text
  6. MOUNJARO (tirzepatide) injection and KwikPen — current label (revised 8/2026). DailyMed (U.S. National Library of Medicine), August 2026. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=d2d7da5d-ad07-4228-955f-cf7e355c8cc0. Accessed November 2, 2026. Back to the text
  7. Ozempic (semaglutide injection) product monograph. Health Canada Drug Product Database / Novo Nordisk Canada, April 14, 2026. https://pdf.hres.ca/dpd_pm/00084255.PDF. Accessed November 2, 2026. Back to the text
  8. Zepbound (tirzepatide injection) KwikPen product monograph. Health Canada Drug Product Database / Eli Lilly Canada, April 2, 2026. https://pdf.hres.ca/dpd_pm/00084150.PDF. Accessed November 2, 2026. Back to the text

Figures marked “as reported” are historical: they show what the source said on that date, not today's price or rule.

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Substantive corrections are also logged at corrections.

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